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KMID : 0811820090130020235
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Journal of Korean Society of Pediatric Nephrology
2009 Volume.13 No. 2 p.235 ~ p.241
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Clinical Significance of Bicarbonate Gap in Pediatric Patients with Acute Gastroenteritis
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Park Kyu-Hee
Jung Seong-Kwan
Yim Hyung-Eun
Yoo Kee-Hwan
Hong Young-Sook
Lee Joo-Won
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Abstract
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Purpose : The purpose of this study was to determine the clinical value of bicarbonate gap (BG) in acute gastroenteritis by comparison of clinical manifestations and laboratory findings.
Methods : We retrospectively analyzed 135 patients who had acute gastroenteritis. We classified them into two groups: BG■-5 (group A), BG>-5 (group B). We made a comparative study for clinical manifestations, serum electrolyte, albumin, protein, blood urea nitrogen (BUN), creatinine, anion gap (AG), delta anion gap (■AG) and delta bicarbonate (■HCO3-) between the two groups.
Results : The duration of hospitalization and diarrhea was significantly longer in group A than group B. In laboratory findings, serum sodium, serum total CO2, total protein, AGcorrected and ■AG were lower in group A than group B. ■HCO3- and chloride were higher in group A than group B.
Conclusion : BG may be a sensitive predictor enough to access the severity of acute gastroenteritis.
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KEYWORD
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Acute gastroenteritis, Metabolic acidosis, Delta anion gap, Delta bicarbonate
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